All children diagnosed with various degrees of malnutrition responded immunologically to

ChiroRab™ by producing RVNA titers well above the acceptable level of 0.5 IU/mL by Day 14.

Protein energy malnutrition (PEM) as defined by the Indian Academy of Pediatrics:

  • Grade I: Children between 71 and 80% of the normal percent of standard weight for age.
  • Grade II: Children between 61 and 70% of the normal percent of standard weight for age.
  • Grade III: Children between 51 and 60% of the normal percent of standard weight for age.
  • Grade IV: Children below 50% of the normal percent of standard weight for age.

References:

1.Huang G, Liu H, Cao Q, et. al., Safety of post-exposure rabies prophylaxis during pregnancy: a follow-up study from Guangzhou, China. Hum Vaccin Immunother. 2013 Jan;9(1):177-83.

2.Data on file. Deshpande A, Briggs DJ. Rabies vaccination in immunosuppressed patients. In:Dodet E, Meslin FX, Heseltine E, eds. Rabies Control in Asia. Proceedings of the Fourth International Symposium on Rabies Control in Asia, Hanoi, Vietnam, 5–9 March 2001:John Libbey Eurotext,Paris:58–60.

3.Sampath, G, et al. Rabies post-exposure prophylaxis in malnourished children exposed to suspect rabid animals. Vaccine. 2005;23(9), 1102–1105.